_Overview
Aging is a major risk factor for many human diseases. It is a complex process that progressively compromises most of the biological functions of the organisms, resulting in an increased susceptibility to disease and death.
In the last decade, there was an increase in research about the role of cellular metabolism in controlling longevity. Several metabolic changes accumulate with age, indicating the presence of a “metabolic clock”. They could be the basis to develop new strategies to treat age-related diseases like metabolic, neurodegenerative, cardiovascular, and degenerative joint diseases…
In this symposium, we will focus on the last discovered about several hallmarks of aging: genomic instability, telomerase attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis.
It will help to know how aging impact on health and the newly emerging findings on the cellular aging hold great promise for improving the quality of life.
_Speakers
Metabolism and Cell Signaling Lab
Spanish National Cancer Research Center (CNIO)
Madrid, Spain
Precision Nutrition and Cancer Program, IMDEA Food Institute
Campus of International Excellence UAM+CSIC
Madrid, Spain
Laboratory of Molecular and Genetic Cardiovascular Pathophysiology
Spanish National Centre for Cardiovascular Research (CNIC)
Madrid, Spain
Laboratory of Retrovirology and Viral Immunopathogenesis
Hospital Clinic i Provincial. Universitat de Barcelona
Barcelona, Spain
Cellular Stress in Health and Disease Lab
Karolinska Institute, Department of Bioscience and Nutrition
Huddinge, Sweden
Department of Molecular and Comparative Pathobiology
Johns Hopkins University School of Medicine
Baltimore, USA
Center for Research in Molecular Medicine and Chronic Disease (CIMUS)
Health Research Insitute of Santiago de Compostela (IDIS)
Universidade de Santiago de Compostela, Spain
Neurobiology Experimental Group
IRYCIS-Hospital Ramón y Cajal. UCM
Madrid, Spain
Freshage Research Group
Faculty of Physiology. University of Valencia
Valencia, Spain
Aging and Cancer Lab
Vall d’Hebron Institute of Oncology (VHIO)
Barcelona, Spain
Epigenetic Unit, Rheumatology Research Group
Biomedical Research of A Coruña (INIBIC)
A Coruña, Spain
Cellular Plasticity in Age-related Pathologies
Institut Pasteur
Paris, France
Department of Pharmacology, Pharmacy and Pharmaceutical Technology, I+D Farma Group, Facultad de Farmacia, Instituto de Materiales (iMATUS)
Health Research Institute of Santiago de Compostela (IDIS)
Universidade de Santiago de Compostela, Spain
_Scientific committee
Laboratory of Cellular Senescence, Cancer and Ageing
Health Research Institute of
Santiago de Compostela (IDIS), Spain
Health Research Institute of Santiago de Compostela (IDIS)
Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Cellular Therapy and Regenerative Medicine Group
CICA-INIBIC
Universidade da Coruña, Spain
Cartilage Biology Unit, Rheumatology Research Group
Biomedical Research of A Coruña (INIBIC), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Gene and Cell Therapy Research Group (G-CEL)
Interdisciplinary Center for Chemistry and Biology (CICA)
Universidade da Coruña, Spain
Laboratory of Glia-Neuron Interactions in the Control of Hunger
Achucarro Basque Center for Neuroscience
Leioa, Spain
_Scientific committee
Laboratory of Cellular Senescence, Cancer and Ageing
Health Research Institute of
Santiago de Compostela (IDIS), Spain
Health Research Institute of Santiago de Compostela (IDIS)
Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Cellular Therapy and Regenerative Medicine Group
CICA-INIBIC
Universidade da Coruña, Spain
Cartilage Biology Unit, Rheumatology Research Group
Biomedical Research of A Coruña (INIBIC), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Gene and Cell Therapy Research Group (G-CEL)
Interdisciplinary Center for Chemistry and Biology (CICA)
Universidade da Coruña, Spain
Laboratory of Glia-Neuron Interactions in the Control of Hunger
Achucarro Basque Center for Neuroscience
Leioa, Spain
_Scientific committee
Laboratory of Cellular Senescence, Cancer and Ageing
Health Research Institute of
Santiago de Compostela (IDIS), Spain
Health Research Institute of Santiago de Compostela (IDIS)
Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Cellular Therapy and Regenerative Medicine Group
CICA-INIBIC
Universidade da Coruña, Spain
Cartilage Biology Unit, Rheumatology Research Group
Biomedical Research of A Coruña (INIBIC), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Gene and Cell Therapy Research Group (G-CEL)
Interdisciplinary Center for Chemistry and Biology (CICA)
Universidade da Coruña, Spain
Laboratory of Glia-Neuron Interactions in the Control of Hunger
Achucarro Basque Center for Neuroscience
Leioa, Spain
_Agenda
17th July
9:00
Opening the event
Moderator: Professor María Arufe
10:00
Nutrient - Rag GTPase signaling at the crossroads of cancer and aging
Dr. Alejo Efeyan
11:00
Stem cell-derived extracellular vesicles and healthy aging
Professor Consuelo Borrás
12:00
Coffee break and poster exhibition
Moderator: Dr Beatriz Caramés
12:30
The National strategy on persozalized Medicine: The IMPaCT program
Professor Ángel Carracedo
13:30
Cardiovascular disease in Hutchinson-Gilford progeria syndrome: from pathological mechanisms to therapies
Professor Vicente Andrés García
14:30
Lunch break and poster exhibition
18th July
Moderator: Dr. Jesús Mateos Martín
9:00
Senolytics decreased both cellular senescence and viral levels in an ex vivo model from people living with HIV
Dr. Nuria Climent
10:00
Senescence and cellular plasticity in health and disease
Professor Han Li
11:00
Iron accumulation drives fibrosis, senescence, and the senescence-associated secretory phenotype
Dr. Mate Maus
12:00
Coffee break and poster exhibition
Moderator: Professor Susana Sangiao
12:30
YAP as master regulator in cancer
Dr. María Elena Rendueles García Rodríguez
13:30
Can we rejuvenate the brain cells?
Jose Antonio Rodriguez Navarro
14:30
Lunch break and poster exhibition
19th July
Moderator: Dr. Manuel Collado
10.00
Epigenetic mechanisms underlying the pathogenesis of osteoarthritis
Dr. M. Carmen de Andrés González
11.00
Targeting polyamines metabolism to counteract detrimental features of senescent cells
Professor Federico Pietrocola
12:00
Coffee break and poster exhibition
Moderator: Dr. Ana Rey Rico
12.30
From the nanoscale to microscale: strategies to manage age-related diseases
Dr. Patricia Díaz Rodríguez
13.30
EV-Tag: A new synthetic reporter system to understand in vivo cell type specific extracellular vesicles in metabolic health and disease
Dr. Marta García Contreras
14.30
Award to the best flash talk and poster
Moderators:
Professor María Arufe
Dr. Juan A. Fafián Labora
16:00
Flash Talks
17:00
Deciphering cell health and metabolism changes with new Bioluminescent tools
Dr. María Jurado
Promega Biotech Ibérica S.L.
17:30
Flash Talks
18:30
Poster exhibition
Moderators:
Professor María Arufe
Dr. Juan A. Fafián Labora
16:00
Flash Talks
18:00
Poster exhibition
Participants:
PI/Postdoc/PhD students/Master students/Degree students/Public
Abstract Submission:
Send an email to contact@cams2023.net indicating:
- Title of work
- Authors and affiliation
- Abstract of work.
Rules for presentations:
Flash talk: 10 minutes per talk
Poster:
- Size: Landscape 70 x 50 cm.
- File Formats allowed: PDF, JPG, TIFF, PNG
- Image Resolution: 300 ppp
Deadline:
Extended to 7th June 2023
_Abstract submission
_Organization
Dr. Juan Fafián Labora
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña. Spain
Professor María Arufe
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña. Spain
Assistance to organization:
Rocío Mato Basalo
PhD Student. TCMR Group. CICA-INIBIC
Universidade da Coruña. Spain
Sergio Lucio Gallego
PhD Student. TCMR Group. CICA-INIBIC
Universidade da Coruña. Spain
Ismael López Calvo
Degree student. TCMR&EXPRELA Group. CICA-INIBIC
Universidade da Coruña. Spain
Carmen Alarcón-Veleiro
Master student. TCMR Group. CICA-INIBIC
Universidade da Coruña. Spain
Alba Iglesias Fente
PhD Student. G-CEL Group CICA
Universidade da Coruña. Spain
_Getting there
2A
12- 12A- 17- 22
Stop at Hospital de Oza.
6 min. walking
Stop at Avda. da Pasaxe. Viaducto.
12 min. walking
Nearest Taxi stop: Hospital de Oza
Xubias de Arriba, 5, A Coruña
6 min. walking
CAMS 2023
17-19 July 2023
Facultad de Fisioterapia
UDC Campus de Oza
15006 A Coruña
Galicia Spain
_Funding entities
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